ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,950, issued on July 7, was assigned to Spring Works Therapeutics Inc. (Stamford, Conn.), THE KATHOLIEKE UNIVERSITEIT LEUVEN (Vlaams-Brabant Leuven, Belgium) and VIB vzw (Ghent, Belgium).

"Spiros and related analogs for inhibiting YAP/TAZ-TEAD" was invented by Bart Vanderhoydonck (Diest, Belgium), Arnaud Marchand (Bierbeek, Belgium), Aurelie Candi (Werchter, Belgium) and Matthias Versele (Kessel-Lo, Belgium).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to spiro-fused tetrahydroquinazoline compounds, to the compounds for use as a medicine, more in particular for the prevention or treatment of diseases mediated by activit...