US Patent Issued to SPINALCYTE on March 17 for "Inhibition of TNF-alpha by fibroblasts and fibroblast exosomes" (California, Texas Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,112, issued on March 17, was assigned to SPINALCYTE LLC (Houston).

"Inhibition of TNF-alpha by fibroblasts and fibroblast exosomes" was invented by Pete O'Heeron (Houston) and Thomas Ichim (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are means of suppressing production of the inflammatory cytokine TNF-alpha through contact-dependent and contact-independent means by fibroblast populations and products and/or derivatives of fibroblast populations. In one embodiment, fibroblasts are cultured under conditions allowing proliferation of said fibroblasts, wherein said proliferative status of fibroblasts correlates with the ability t...