US Patent Issued to Sophia Genetics on July 7 for "Methods for DNA library generation to facilitate the detection and reporting of low frequency variants" (Swiss Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,158, issued on July 7, was assigned to Sophia Genetics S.A. (Rolle, Switzerland).

"Methods for DNA library generation to facilitate the detection and reporting of low frequency variants" was invented by Morgane Macheret (Saint-Sulpice, Switzerland), Christian Pozzorini (Saint-Sulpice, Switzerland), Adrian Willig (Saint-Sulpice, Switzerland), Jonathan Bieler (Saint-Sulpice, Switzerland) and Zhenyu Xu (Saint-Sulpice, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods are disclosed for adding adapters to fragmented nucleic acids for next generation sequencing, including providing numerical codes based on variable adapter molecular barcod...