ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,727,970, issued on Sept. 8, was assigned to Smylio Inc. (Fremont, Calif.).

"Orthodontic devices for delivery of an active agent" was invented by Loc Phan (Santa Clara, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Devices configured for insertion into an oral cavity of a subject for delivery of an agent for a time period are described. The devices are comprised of at least two polymer shells that nest or stack to create a space or gap therebetween. The agent is placed in the gap and is released in a controlled fashion to deliver agent for the time period. Kits comprised of a device and optionally a refill of the agent are also described."

The p...