US Patent Issued to SIGNABLOK on Nov. 3 for "Methods for targeted imaging with spherical rHDLs" (Massachusetts Inventor)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,779,061, issued on Nov. 3, was assigned to SIGNABLOK INC. (Shrewsbury, Mass.).

"Methods for targeted imaging with spherical rHDLs" was invented by Alexander B. Sigalov (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A new approach to targeting imaging agents to macrophage-rich sites of interest is disclosed. Compositions of the invention are rHDL and HDL-like liposomal compositions, protein constituents of which, apolipoproteins A-I and/or A-II or fragments thereof are used not only as structural but also as targeting agents. This is achieved by certain controlled chemical or enzymatic modification of apolipoproteins A-I or A-II or fragm...