ALEXANDRIA, Va., May 12 -- United States Patent no. 12,622,921, issued on May 12, was assigned to SHORLA PHARMA LTD. (County Tipperary, Ireland).
"Stable formulations comprising thiotepa" was invented by Sharon Cunningham (County Tipperary, Ireland), Orlaith Ryan (County Tipperary, Ireland) and Johannes Jan Platteeuw (Boxtel, Netherlands).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides pharmaceutical compositions comprising thiotepa and one selected from PEG, such as PEG400 or PEG600, and DMSO, and optionally water or an aqueous saline solution and thiosulfate. The composition is free or substantially free of impurities. Also provided is a method for treating cancer in a subject...