ALEXANDRIA, Va., April 15 -- United States Patent no. 12,599,685, issued on April 14, was assigned to SHANGHAI UNIVERSITY OF MEDICINE & HEALTH SCIENCES (Shanghai).

"Tumor stroma imaging agent and preparation method thereof" was invented by Gang Huang (Shanghai) and Bin Li (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "A tumor stroma imaging agent with a chemical structural formula (I):is provided, where R is hydrogen or fluorine. Compared with the prior art, the tumor stroma imaging agent exhibits significant affinity for fibroblast activation protein (FAP), high uptake for a malignant tumor with high FAP expression in a tumor stroma, and high sensitivity and specificity for the diagnosis of a mali...