US Patent Issued to SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES on Oct. 6 for "Method for modulating RNA splicing by inducing base mutation at splice site or base substitution in polypyrimidine region" (Chinese Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,420, issued on Oct. 6, was assigned to SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES (Shanghai).

"Method for modulating RNA splicing by inducing base mutation at splice site or base substitution in polypyrimidine region" was invented by Xing Chang (Shanghai), Juanjuan Yuan (Shanghai) and Yunqing Ma (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a method for modulating RNA splicing by inducing a base mutation at a splice site or a base substitution in a polypyrimidine region. The method comprises expressing a targeting cytosine deaminase in a cell, to induce AG at a 3' splice site of an intron of intere...