ALEXANDRIA, Va., May 26 -- United States Patent no. 12,637,714, issued on May 26, was assigned to SEQUENOM Inc. (San Diego).

"Methods, and systems to detect transplant rejection" was invented by Roy Brian Lefkowitz (San Diego), John Allen Tynan (San Diego) and Chen Xu (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "This application provides methods and systems for determining transplant status. In some embodiments, the method comprises obtaining a biological sample from an organ transplant recipient who has received an organ; isolating cell-free nucleic acids from the biological sample; measuring the amount of each allele of one or more polymorphic nucleic acid targets in the biological sample; ide...