US Patent Issued to Scribe Therapeutics on Feb. 24 for "Engineered guide scaffolds" (California Inventors)

ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,743, issued on Feb. 24, was assigned to Scribe Therapeutics Inc. (Alameda, Calif.).

"Engineered guide scaffolds" was invented by Gayathri Vijayakumar (Oakland, Calif.), Sean Higgins (Alameda, Calif.), Isabel Colin (Oakland, Calif.), Sarah Denny (San Francisco), Brett T. Staahl (Tiburon, Calif.), Benjamin Oakes (El Cerrito, Calif.), Angus Sidore (Oakland, Calif.) and Suraj Makhija (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are engineered Class 2. Type V nucleases and guide RNAs useful for the editing of target nucleic acids. Also provided are methods of making and using such variants to modify nucleic acids."

The p...