ALEXANDRIA, Va., July 14 -- United States Patent no. 12,682,458, issued on July 14, was assigned to SCREEN Holdings Co. Ltd. (Kyoto, Japan) and Cyfuse Biomedical K.K. (Tokyo).
"Quality evaluation method for spheroid including hepatocytes" was invented by Ryo Hasebe (Kyoto, Japan), Toshihiko Maekawa (Tokyo) and Ayu Inoue (Tokyo).
According to the abstract* released by the U.S. Patent & Trademark Office: "In an evaluation method, first, spheroids obtained by three-dimensional culture of multiple kinds of liver-derived cells are imaged by optical coherence photography, a localization region is extracted from the photographic image, the localization region is analyzed (analysis step), and the condition of the spheroid is evaluated. The analys...