ALEXANDRIA, Va., June 2 -- United States Patent no. 12,643,911, issued on June 2, was assigned to SCINOPHARM TAIWAN LTD. (Tainan, Taiwan).
"Process for preparing Relugolix and intermediates thereof" was invented by Yung-Hung Chang (Tainan, Taiwan), Tsung-Yu Hsiao (Tainan, Taiwan) and Meng-Fen Ho (Tainan, Taiwan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides improved processes for the preparation of Relugolix and intermediates thereof. Relugolix is prepared via intermediates (M7) and (M8):wherein X is as described herein. Present disclosure also provides three additional routes to prepare Relugolix and intermediates thereof, where the starting material of ethyl 2-amino-4-methyl...