US Patent Issued to Scholar Rock on Oct. 6 for "TGFbeta1-binding immunoglobulins and use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,226, issued on Oct. 6, was assigned to Scholar Rock Inc. (Cambridge, Mass.).

"TGFbeta1-binding immunoglobulins and use thereof" was invented by Thomas Schurpf (Cambridge, Mass.), Gregory J. Carven (Cambridge, Mass.), Abhishek Datta (Cambridge, Mass.) and Kimberly Long (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are immunoglobulins, such as antibodies, and antigen binding portions thereof, that specifically bind complexes of GARP-TGFBeta1, LTBP1-TGFBeta1, LTBP3-TGFBeta1, and/or LRRC33-TGFBeta1. The application also provides methods of use of these immunoglobulins for, for example, inhibiting TGFBeta1 activity, and...