US Patent Issued to Salk Institute for Biological Studies on March 31 for "Oncolytic adenovirus compositions" (California Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,589,128, issued on March 31, was assigned to Salk Institute for Biological Studies (La Jolla, Calif.).

"Oncolytic adenovirus compositions" was invented by Clodagh O'Shea (San Diego) and Shigeki Miyake-Stoner (La Jolla, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "An adenovirus comprising an E1A polypeptide comprising one or more modifications and comprising an E4orf6/7 polypeptide comprising one or more modifications is described. Compositions and kits comprising the modified adenoviruses are also described. Further described is a method of treating a proliferative disorder in a subject comprising administering to the subject an adenovirus com...