US Patent Issued to Saint Joseph's University on July 28 for "Allosteric agonists and positive allosteric modulators of Glucagon-like peptide 1 receptor" (Pennsylvania, Maryland Inventors)

ALEXANDRIA, Va., July 28 -- United States Patent no. 12,691,118, issued on July 28, was assigned to Saint Joseph's University (Philadelphia).

"Allosteric agonists and positive allosteric modulators of Glucagon-like peptide 1 receptor" was invented by Zhijun Li (Bala Cynwyd, Pa.), Tejashree Redij (Warrington, Pa.), James McKee (Havertown, Pa.), Zhiyu Li (Woodstock, Md.) and Jeffrey Campbell (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the discovery of small molecule compounds that act as GLP-1R agonists and/or as positive allosteric modulators (PAMs) of GLP-1R. Such compounds are useful to treat, ameliorate, and/or prevent insulin resistance and/or diabetes in ...