ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,085, issued on March 24, was assigned to River BioMedics B.V. (Enschede, Netherlands).

"Microfluidic device for a 3D tissue structure" was invented by Marcelo Catarino Ribeiro (Amersfoot, Netherlands) and Tom Mathijs Paulus Maria Boonen (Enschede, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "Microfluidic device comprising at least one cell culture unit for forming, culturing, growing and/or maintaining a 3D tissue structure such as a 3D strip of cardiac tissue, wherein the at least one cell culture unit comprises: a respective culture chamber for culturing cells having a chamber outlet opening; and a cell supply channel arranged to gu...