ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,742,151, issued on Sept. 22, was assigned to Ricoh Co. Ltd. (Tokyo) and Elixirgen Scientific Inc. (Baltimore).
"Production method for microglia" was invented by Masayuki Yumoto (Kanagawa, Japan), Yudai Kawashima (Kanagawa, Japan), Hikaru Watanabe (Kanagawa, Japan), Toshihiko Hosoya (Tokyo) and Minoru Ko (Tokyo).
According to the abstract* released by the U.S. Patent & Trademark Office: "There is provided a production method for microglia, including a step of introducing, into pluripotent stem cells, a nucleic acid including an open reading frame of a transcription factor that increases expression of a Complement C3 (C3) gene. In the production method, the transcription factor is sel...