ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,748, issued on April 14, was assigned to RICHTER GEDEON NYRT. (Budapest, Hungary).
"Affinity chromatography of immunoglobulins by using pre-capture flocculation" was invented by Zsuzsanna Keszey (Veszprem, Hungary) and Zoltan Suto (Fehergyarmat, Hungary).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to new methods for the purification of immunoglobulins from cell culture harvest. These methods are characterized by cleaning steps preceding an initial capture chromatography step. Preferably, the initial capture chromatography is an affinity chromatography and the pre-capture cleaning effect is obtained by flocculation an...