ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,748,114, issued on Sept. 29, was assigned to Rhode Island Hospital (Providence, R.I.).

"Diagnosis, prognosis and treatment of malignant neoplasms" was invented by Jack R. Wands (Warwick, R.I.), Rolf I. Carlson (Westwood, Mass.) and Xiaoqun Dong (East Greenwich, R.I.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to antibodies and derivatives that bind the full-length isoform of aspartate beta-hydroxylase (ASPH) and uses thereof. The antibodies and derivatives are useful in compositions and methods for detecting and/or treating a malignant neoplasm in a subject and for predicting subsequent complications of untreated progression ...