ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,558,330, issued on Feb. 24, was assigned to RESQ Pharmaceuticals LLC (Orange, Calif.).

"Methods and compositions for treating edema refractory to oral diuretics" was invented by Balasingam Radhakrishnan (Chapel Hill, N.C.), Ben Esque (Huntington Beach, Calif.), Wei Lin (San Diego) and Andrew Xian Chen (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention features methods and compositions for the intranasal, sublingual, and subcutaneous administration of bumetanide for the treatment of subjects suffering from edema refractory to oral diuretics."

The patent was filed on May 14, 2025, under Application No. 19/208,335.

*For furth...