ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,863, issued on Feb. 24, was assigned to RESQ BIOTECH (Patra, Greece).

"Macrocyclic modulators of disease associated protein misfolding and aggregation" was invented by Georgios Skretas (Athens, Greece).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the present invention disclose compounds that modulate the aggregation of amyloidogenic proteins or peptides. In some aspects, disclosed compounds modulate the aggregation of disease-associated proteins and natural Beta-amyloid peptides. In a preferred embodiment, the compounds can inhibit natural amyloid aggregation. Pharmaceutical compositions comprising the compounds of the embodiments, and d...