ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,207, issued on March 17, was assigned to RESEARCH TRIANGLE INSTITUTE.
"Indazole derivatives as cannabinoid receptor partial agonists" was invented by George Amato (Cary, N.C.), Rangan Maitra (Cary, N.C.) and Scott P. Runyon (Hillsborough, N.C.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure includes peripheral partial agonists of one or more CB receptors, including modulation of CB1, both with and without CB2 selectivity. The compounds of the present disclosure may be useful in the treatment of diseases and disorders mediated by a CB-signaling pathway, including but not limited to pain, gastrointestinal disorders, metabolic di...