ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,633, issued on March 3, was assigned to Replimune Ltd. (Oxford, Great Britain).
"Oncolytic virus strain" was invented by Robert Stuart Coffin (London).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an oncolytic virus which is, or is derived from, a clinical isolate which has been selected by comparing the abilities of a panel of three or more clinical isolates of the same viral species to kill tumor cells of two or more tumor cell lines in vitro and selecting a clinical isolate which is capable of killing cells of two or more tumor cell lines more rapidly and/or at a lower dose in vitro than one or more of the other c...