US Patent Issued to REMD Biotherapeutics on April 21 for "Antibodies which bind human endothelin receptor a (ET a R)" (California Inventors)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,631, issued on April 21, was assigned to REMD Biotherapeutics Inc (Camarillo, Calif.).

"Antibodies which bind human endothelin receptor a (ET a R)" was invented by Hai Yan (Thousand Oaks, Calif.) and John Zhang (Camarillo, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This application provides isolated antibodies, and antigen-binding fragments thereof, that specifically bind endothelin A receptor (ETAR). These ETAR antibodies, or antigen-binding fragments thereof, have a high affinity for ETAR, function to effectively block ET-1 binding to ETAR, are less immunogenic compared to their unmodified parent antibodies in a given species (e.g., in...