US Patent Issued to REGENXBIO on March 3 for "Methods of size exclusion chromatography for the characterization of recombinant adeno-associated virus compositions" (Maryland Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,645, issued on March 3, was assigned to REGENXBIO INC. (Rockville, Md.).

"Methods of size exclusion chromatography for the characterization of recombinant adeno-associated virus compositions" was invented by Li Zhi (Bethesda, Md.) and Zhuchun Wu (North Potomac, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to using size exclusion chromatography to isolate AAV genome, to determine the vector genome size purity of a composition comprising isolated rAAV particles, to assess the folding or secondary structure of vector genomes inside the capsids, and to determine vector genome titer (Vg) of a composition comprising is...