US Patent Issued to Regents of the University of Minnesota on Sept. 1 for "Anti-DR5 polypeptides and methods of use thereof" (Minnesota Inventors)

ALEXANDRIA, Va., Sept. 1 -- United States Patent no. 12,723,094, issued on Sept. 1, was assigned to Regents of the University of Minnesota (Minneapolis).

"Anti-DR5 polypeptides and methods of use thereof" was invented by Benjamin Hackel (Minneapolis), Jonathan N. Sachs (Minneapolis) and Nagamani Vunnam (Minneapolis).

According to the abstract* released by the U.S. Patent & Trademark Office: "Certain embodiments of the invention provide helix sequences that have affinity for Death Receptor 5 (DR5). Certain embodiments of the invention provide an isolated anti-DR5 polypeptide (e.g., affibody for DR5) that modulates the activity and/or conformation of DR5. Certain embodiments of the invention provide methods of noncompetitively inhibiting DR...