US Patent Issued to Regents of the University of Minnesota on July 7 for "Methods for the evaluation of neutralizing antibodies for adeno-associated virus" (Minnesota Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,178, issued on July 7, was assigned to Regents of the University of Minnesota (Minneapolis).

"Methods for the evaluation of neutralizing antibodies for adeno-associated virus" was invented by Georgiy Aslanidi (Minneapolis) and Karina Krotova (Minneapolis).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure describes a method that includes using dorsomorphin to increase the infectivity of adeno-associated virus (AAV). The AAV may be of any AAV serotype. In some embodiments, dorsomorphin may be used in combination with IL-6 or TNFAlpha or both. This disclosure further describes methods for using dorsomorphin-treated cells to determine neutral...