ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,300, issued on Sept. 29, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).
"Methods and antibody compositions for tumor treatment" was invented by Eric Smith (New York), Samuel Davis (New York), Bindu Varghese (Hopewell Junction, N.Y.), Jessica R. Kirshner (New York) and Gavin Thurston (Briarcliff Manor, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides bispecific antibodies that bind to CD3 and tumor antigens and methods of using the same. According to certain embodiments, the bispecific antibodies of the invention exhibit reduced effector functions and have a unique binding profile with regard to F...