US Patent Issued to Regeneron Pharmaceuticals on Sept. 15 for "MAGE-A4 T cell receptors and methods of use thereof" (New York Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,469, issued on Sept. 15, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"MAGE-A4 T cell receptors and methods of use thereof" was invented by Natalie Bowerman (Tarrytown, N.Y.), Cagan Gurer (Tarrytown, N.Y.) and Johanna Hansen (Tarrytown, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides isolated T cell receptors (TCRs) that specifically bind to an HLA-displayed cancer testis antigen Melanoma-Associated Antigen A4 (MAGE-A4) peptide, as well as therapeutic and diagnostic methods of using those isolated TCRs. The present invention provides T cell receptors (TCRs) that were generated against a MAGE-A...