US Patent Issued to Regeneron Pharmaceuticals on May 19 for "Humanized universal light chain mice" (North Carolina, New York, California Inventors)

ALEXANDRIA, Va., May 19 -- United States Patent no. 12,628,801, issued on May 19, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Humanized universal light chain mice" was invented by John McWhirter (Greenville, N.C.), Lynn Macdonald (Harrison, N.Y.), Sean Stevens (Del Mar, Calif.), Andrew J. Murphy (Croton-on-Hudson, N.Y.) and Margaret Karow (Santa Rosa Valley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Mice, tissues, cells, and genetic material are provided that comprise a humanized heavy chain immunoglobulin locus, a humanized light chain locus that expresses a universal light chain, and a gene encoding an ADAM6 or ortholog or homolog or functional fragment thereof. Mice are ...