US Patent Issued to Regeneron Pharmaceuticals on March 3 for "CHO integration sites and uses thereof" (New York Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,667, issued on March 3, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"CHO integration sites and uses thereof" was invented by Ying Shen (Yorktown Heights, N.Y.), Darya Burakov (Tarrytown, N.Y.), Gang Chen (Yorktown Heghts, N.Y.) and James P. Fandl (LaGrangeville, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Expression-enhancing nucleotide sequences for eukaryotic expressions systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Genomic integration sites providing enhanced expression and methods of use thereof are provided for expression of a gene of interest in a e...