US Patent Issued to REGENERON PHARMACEUTICALS on April 21 for "Protein-drug conjugates comprising camptothecin analogs and methods of use thereof" (Delaware Inventor)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,605,459, issued on April 21, was assigned to REGENERON PHARMACEUTICALS INC. (Tarrytown, N.Y.).

"Protein-drug conjugates comprising camptothecin analogs and methods of use thereof" was invented by Amy Han (Hockessin, Del.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are protein-drug conjugates and compositions thereof that are useful, for example, for target-specific delivery of therapeutic moieties, e.g., camptothecin analogs and/or derivatives. In certain embodiments, provided are specific and efficient methods for producing protein-drug constructs (e.g., antibody-drug conjugates) utilizing a combination of transglutaminase and 1,3-...