ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,278, issued on April 7, was assigned to REATA PHARMACEUTICALS INC (Irving, Texas).

"Biaryl amides with modified sugar groups for treatment of diseases associated with heat shock protein pathway" was invented by Xin Jiang (Coppell, Texas), Melean Visnick (Irving, Texas), Christopher F. Bender (Garland, Texas), Gary Bolton (Ann Arbor, Mich.), Bradley Caprathe (Livonia, Mich.) and Chitase Lee (Ann Arbor, Mich.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are biaryl amides and coumarin-based compounds with modified sugar groups having the formulas:wherein variables are as defined herein. Pharmaceutical compositions of the compounds are...