ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,222, issued on Sept. 29, was assigned to Ramot at Tel-Aviv University Ltd. (Tel Aviv, Israel) and The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).
"Chemiluminescence probes for tuberculosis" was invented by Doron Shabat (Tel Aviv, Israel), Ori Green (Tel Aviv, Israel) and Matthew Bogyo (Redwood City, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Turn-ON dioxetane-based chemiluminescence probes based on the Schapp's adamantylidene-dioxetane probe are useful for determining the presence, or measuring the level, of Mycobacterium tuberculosis (Mtb)-specific protease in a sample, and for assessing the susceptibi...