ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,578, issued on April 21, was assigned to QILU PHARMACEUTICAL Co. LTD. (Jinan, China).
"Crystal form of spirocyclic amine aryl phosphorus oxide compound and preparation method therefor" was invented by Zhaofeng Ding (Jinan, China) and Qiang Fu (Jinan, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a crystal form of a compound of Formula (I), i.e. (2-((5-chloro-2-((2-methoxy-4-(9-methyl-3,9-diaza-spiro[5.5]undecan-3-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide. The present invention further relates to a pharmaceutical composition of the crystal form, and the pharmaceutical use thereof and ...