US Patent Issued to Provincial Health Services Authority, Universite Laval on March 24 for "Compositions and methods for enhanced lymphocyte-mediated immunotherapy" (Canadian Inventors)

ALEXANDRIA, Va., March 24 -- United States Patent no. 12,582,699, issued on March 24, was assigned to Provincial Health Services Authority (Vancouver, Canada) and Universite Laval (Quebec, Canada).

"Compositions and methods for enhanced lymphocyte-mediated immunotherapy" was invented by Julian J. Lum (Victoria, Canada), Lindsay Devorkin (Burnaby, Canada), Yannick Doyon (Quebec, Canada) and Gillian Carleton (Victoria, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "Lymphocytes having a suppressed autophagy gene useful in immunotherapy are disclosed. The lymphocytes can express an antigen targeting receptor such as a chimeric antigen receptor (CAR) or endogenous or engineered T-cell receptor to target ce...