US Patent Issued to Providence Health & Services-Oregon on Sept. 8 for "T cell receptors specific for a mutant form of the RET oncogene and uses thereof" (Oregon Inventors)

ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,370, issued on Sept. 8, was assigned to Providence Health & Services-Oregon (Portland, Ore.).

"T cell receptors specific for a mutant form of the RET oncogene and uses thereof" was invented by Eric Tran (Portland, Ore.) and Yi-Ping Shih (Portland, Ore.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Isolated T cell receptors (TCRs) that specifically recognize a peptide derived from a mutant form of RET (M918T) are described. The TCRs include an alpha chain variable region and a beta chain variable region having the complementarity determining regions (CDRs) of an alpha chain variable region and beta chain variable region of a TCR isolated from a pati...