US Patent Issued to PROTHENA BIOSCIENCES on Sept. 22 for "Methods for detecting phosphorylated alpha-synuclein" (California Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,742,789, issued on Sept. 22, was assigned to PROTHENA BIOSCIENCES Ltd. (Dublin).

"Methods for detecting phosphorylated alpha-synuclein" was invented by Robin Barbour (Walnut Creek, Calif.), Lynn R. Zieske (Livermore, Calif.) and Sarah Hamren (Martinez, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides methods of detecting alpha-synuclein using a capture antibody and a reporter antibody. The capture antibody binds preferentially to full-length alpha-synuclein phosphorylated at residue 129 (PS129 alpha-synuclein) over unphosphorylated full-length alpha-synuclein. The 11A5 antibody is an example of a suitable capture antibody. T...