US Patent Issued to PROBIOGEN on June 9 for "Hyperactive transposons and transposases" (German Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,934, issued on June 9, was assigned to PROBIOGEN AG (Berlin).

"Hyperactive transposons and transposases" was invented by Volker Sandig (Berlin), Sven Krugener (Berlin) and Thomas Rose (Berlin).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a polypeptide comprising a piggyBac transposase or a fragment or a derivative thereof having transposase function comprising at least one amino acid substitution. Further, the present invention relates to a transposable element comprising a piggyBac or piggyBac-like left repeat sequence and left internal repeat sequence, wherein the left internal repeat sequence comprises at least on...