US Patent Issued to PRESIDENT AND FELLOWS OF HARVARD COLLEGE on May 12 for "Mutant reverse tetracycline transactivators for expression of genes" (Massachusetts, California Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,362, issued on May 12, was assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE.

"Mutant reverse tetracycline transactivators for expression of genes" was invented by David A. Sinclair (Cambridge, Mass.), Yuancheng Lu (Cambridge, Mass.) and Noah Justin Davidsohn (La Jolla, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are mutant reverse tetracycline transactivator (rtTA) proteins and engineered nucleic acids that encode a mutant rtTA that are useful in regulating gene expression, inducing cellular reprogramming, tissue repair, tissue regeneration, organ regeneration, reversing aging, treating a disease, or any combination ther...