US Patent Issued to Precision BioSciences on Sept. 29 for "Engineered meganucleases having specificity for a recognition sequence in the transthyretin gene" (North Carolina Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,430, issued on Sept. 29, was assigned to Precision BioSciences Inc. (Durham, N.C.).

"Engineered meganucleases having specificity for a recognition sequence in the transthyretin gene" was invented by Cassandra Gorsuch (Durham, N.C.), Jochen Genschel (Raleigh, N.C.), Janel Lape (Wake Forest, N.C.), Derek Jantz (Durham, N.C.) and James Jefferson Smith (Morrisville, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention encompasses engineered meganucleases that bind and cleave a recognition sequence within a TTR gene. The present invention also encompasses methods of using such engineered meganucleases to make genetically-modified ce...