US Patent Issued to Precision BioSciences on Aug. 4 for "Gene editing methods for treating alpha-1 antitrypsin (AAT) deficiency" (North Carolina Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,697,400, issued on Aug. 4, was assigned to Precision BioSciences Inc. (Durham, N.C.).

"Gene editing methods for treating alpha-1 antitrypsin (AAT) deficiency" was invented by James Jefferson Smith (Morrisville, N.C.), John Morris (Raleigh, N.C.), Janel Lape (Wake Forest, N.C.), Cassandra Gorsuch (Hillsborough, N.C.), Paige Scarlett Nemec (Durham, N.C.), Jason Richard Harris (Durham, N.C.) and Wendy Shoop (Durham, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are engineered meganucleases that bind and cleave a recognition sequence within a serine peptidase inhibitor, Clade A, Member 1 (SERPINA1) gene, which encodes alpha-1 antitrypsin (AAT...