US Patent Issued to PHILOCHEM on March 17 for "Conjugates of PSMA-binding moieties with cytotoxic agents" (Swiss Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,154, issued on March 17, was assigned to PHILOCHEM AG (Otelfingen, Switzerland).

"Conjugates of PSMA-binding moieties with cytotoxic agents" was invented by Gabriele Bassi (Otelfingen, Switzerland), Samuele Cazzamalli (Otelfingen, Switzerland), Tony Georgiev (Otelfingen, Switzerland), Aureliano Zana (Otelfingen, Switzerland) and Dario Neri (Otelfingen, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "A conjugate of Formula I or a pharmaceutically acceptable salt thereof, wherein: PB is a PSMA binding moiety which has a molecular weight of below 1000 Da; L1 is a linker covalently attaching PB to Gly-Pro, said linker being a saturated or a ...