US Patent Issued to Pfizer on March 24 for "Method of cell culture" (Massachusetts Inventors)

ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,113, issued on March 24, was assigned to Pfizer Inc. (New York).

"Method of cell culture" was invented by Gregory Walter Hiller (Wakefield, Mass.) and Bhanu Chandra Mulukutla (Lawrence, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of cell culture comprising providing cells in a cell culture medium to start a cell culture process, and, maintaining at least one metabolite selected from 3-(4-hydroxyphenyl)lactate, 4-hydroxyphenylpyruvate, phenyllactate, indolelactate, indolecarboxylic acid, homocysteine, 2-hydroxybutyric acid, isovalerate and formate below a concentration C1 in the cell culture medium, wherein C1 is 3 mM and/or (ii) m...