US Patent Issued to Peking University on March 24 for "Compositions and methods for long term culture of hepatocytes" (Chinese Inventors)

ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,111, issued on March 24, was assigned to Peking University (Beijing).

"Compositions and methods for long term culture of hepatocytes" was invented by Hongkui Deng (Beijing), Chengang Xiang (Beijing) and Yuanyuan Du (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compositions for long-term maintenance of functional hepatocytes in culture, a method for improved maintenance of functional hepatocytes in vitro, and functional hepatocytes cultures according to the methods. The culture compositions include at least: one activator of adenylate cyclase, one TGFBetainhibitor, one Notch inhibitor, one Wnt inhibitor, and/or one BMP inhibit...