ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,671, issued on June 23, was assigned to PEKING UNIVERSITY (China).
"Constructs and methods for preparing circular RNA" was invented by Wensheng Wei (Beijing) and Zongyi Yi (Beijing).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides linear RNA precursors and constructs for preparing circular RNAs (circRNAs) comprising an effector RNA sequence, such as a coding RNA sequence. In some embodiments, the linear RNA comprises from the 5' end to the 3' end: (a) a first portion of an RNA element (e.g., an IRES), (b) an effector RNA sequence, and (c) a second portion of the RNA element, wherein the first and the second portions of ...