ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,744, issued on June 9, was assigned to Pathios Therapeutics Ltd. (Milton, Great Britain).

"N-(pyridin-2-yl)-6,7,8,9-tetrahydro-5h-5,8-epiminocyclohepta[cpyridine-10-carboxamide derivatives and similar compounds as GPR65 modulators for the treatment of cancer" was invented by Tom McCarthy (Abingdon, Great Britain), Alan Naylor (Abingdon, Great Britain), Gavin Milne (Abingdon, Great Britain), David Miller (Abingdon, Great Britain) and Maria Ieva (Abingdon, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds of formula (I) as GPR65 modulators for the treatment of a proliferative disorder, such as e.g. ...