US Patent Issued to PARIS SCIENCES ET LETTRES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE on March 31 for "Split photoactive yellow protein complementation system and uses thereof" (French Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,127, issued on March 31, was assigned to PARIS SCIENCES ET LETTRES (Paris), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris) and SORBONNE UNIVERSITE (Paris).

"Split photoactive yellow protein complementation system and uses thereof" was invented by Arnaud Gautier (Paris) and Alison Tebo (Paris).

According to the abstract* released by the U.S. Patent & Trademark Office: "A complementation system including two fragments of photoactive yellow protein (PYP), or truncated fragments thereof, and its use with a fluorogenic hydroxybenzylidene rhodanine (HBR) analog for detecting interactions between biological molecules of interest, in particular between proteins of interest. Especi...