US Patent Issued to Paolo L. Manfredi on Sept. 22 for "Methods for synthesizing enantiopure (S)-methadone, (R)-methadone, racemic (R,S)-methadone and related analogue substances" (American, Italian Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,741,927, issued on Sept. 22, was assigned to Paolo L. Manfredi (Miami Beach, Fla.).

"Methods for synthesizing enantiopure (S)-methadone, (R)-methadone, racemic (R,S)-methadone and related analogue substances" was invented by Paolo L. Manfredi (Miami Beach, Fla.), Charles E. Inturrisi (New York), Andrea Mattarei (Perarolo di Vigonza, Italy), Marco Banzato (Galzignano Terme, Italy), Alberto Furlan (Padua, Italy), Alberto Ongaro (Campolongo Maggiore, Italy), Brian H. Heasley (Wake Forest, N.C.) and Zachary D. Tucker (Cary, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods for the synthesis of enantiopure (S)-methadone, (R)-methadone, (R,S)-metha...