US Patent Issued to Pacira Pharmaceuticals on Sept. 8 for "Manufacturing of bupivacaine multivesicular liposomes" (California Inventors)

ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,095, issued on Sept. 8, was assigned to Pacira Pharmaceuticals Inc. (San Diego).

"Manufacturing of bupivacaine multivesicular liposomes" was invented by Eran Levy (San Diego), Jeffrey S. Hall (San Diego) and John J. Grigsby Jr. (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments of the present disclosure relate to a new and improved large scale commercial manufacturing process of making bupivacaine multivesicular liposomes (MVLs). Batches of bupivacaine MVLs prepared by the new process have high yields, improved stabilities, and desired particle size distributions."

The patent was filed on March 3, 2026, under Application No. 19/5...